Neuromyelitis optica: a demyelinating disease

Neuromyelitis optica-IgG in childhood inflammatory demyelinating CNS disorders.

OBJECTIVE To determine seroprevalence of neuromyelitis optica (NMO)-IgG in childhood CNS inflammatory demyelinating disorders. METHODS We analyzed demographic, clinical, and radiologic data in a blinded fashion and assessed serum NMO-IgG status for 87 children: 41 with relapsing-remitting multiple sclerosis (RRMS), 17 with NMO, 13 with monophasic/recurrent optic neuritis (ON), 13 with transve...

A Case of Neuromyelitis Optica (Devics' Disease)

ages; according to some authors more commonly young females. Pathologically the disease resembles disseminated sclerosis in that there is demyelinization of axis cylinders. The spinal cord shows such diffuse or multiple disseminated lesions. The optic nerves also present the same type of lesions. Clinically the disease is quite distinct from disseminated sclerosis. It is characterized by an acu...

Neuromyelitis Optica in Children: A Rare Entity

     Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...

Neuromyelitis Optica (Devic's Disease). A Case Report

A case of neuromyelitis optica (Devic's disease).

Neuromyelitis optica is an inflammatory disease of the central nervous system in which there are episodes of inflammation and damage to the myelin that almost exclusively affect the optic nerves and spinal cord. It usually causes temporary blindness, occasionally permanent, in one or both eyes. It can also lead to varying degrees of weakness or paralysis in the legs or arms, loss of sensation, ...